PDX INSIGHTS
PIONEERING CANCER RESEARCH
Breast Collection
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Patient Biomarkers at DiagnosisPDX Biomarkers
Model IDPatient IDPathology Diagnosis
ERPRHER2ERPRHER2Germline BRCA1 StatusGermline BRCA2 StatusPath. Stage
Grade
Clinical Event Pt
Age at Diagnosis
Race
Treatment NaivePatient Treatment
BCM-1500613611+Adenocarcinoma, metastatic, NOS (8140/6)NegativeNegativeNegativeNegativeNegativeNegativeWild TypeWild TypeG3 (Poorly Differentiated)Primary33.91WhiteNoCapecitabine,Carboplatin,Cisplatin,Cyclophosphamide,Doxorubicin,Eribulin,Paclitaxel
BCM-151715035+Infiltrating ductular carcinoma (8521/3)NegativeNegativePositiveNegativeNegativePositiveWild TypeWild TypeIVG3 (Poorly Differentiated)Distant Metastasis30.18White,Hispanic or LatinoNoAdo-Trastuzumab Emtansine,Capecitabine,Docetaxel,Fam-trastuzumab deruxtecan-nxki,Paclitaxel,Pertuzumab,Trastuzumab
HCI-001Y0ACP5+Infiltrating ductal carcinomaNegativeNegativeNegativeNegativeNegativeNegativeNot ReportedNot ReportedIVPrimary39.50WhiteNoAdriamycin,Doxorubicin Liposomal,Paclitaxel
HCI-0020RR2HE+Infiltrating ductal carcinomaNegativeNegativeNegativeNegativeNegativeNegativeNot ReportedNot ReportedIIIAG3 (Poorly Differentiated)Primary61.00WhiteYesZometa
HCI-0033BW6YSInfiltrating ductal carcinomaPositivePositiveNegativePositivePositiveNegativeNot ReportedNot ReportedIIIAG3 (Poorly Differentiated)Primary52.00WhiteYesAnastrazole,Carboplatin,Gemcitabine,Paclitaxel,Tamoxifen
HCI-004N12K3YInfiltrating ductal carcinomaNegativeNegativeNegativeNegativeNegativeNegativeNot ReportedNot ReportedIIAPrimary54.83Hispanic or LatinoYesCytoxan,Docetaxel
HCI-00579NTL6+Mixed carcinomaPositivePositivePositivePositivePositiveNegativeNot ReportedNot ReportedIVMetastasis45.00WhiteNoAromasin,Capecitabine,Carboplatin,Cyclophosphamide,Doxorubicin,Fulvestrant,Gemcitabine,Letrozole,Liposomal Doxorubicin,Paclitaxel,Tamoxifen,Taxotere,Trastuzumab,Vinorebline,Zolendronic Acid
HCI-00679NTL6+Mixed carcinomaPositivePositivePositivePositivePositiveNegativeNot ReportedNot ReportedIVMetastasis45.00WhiteNoAromasin,Capecitabine,Carboplatin,Cyclophosphamide,Doxorubicin,Fulvestrant,Gemcitabine,Letrozole,Liposomal Doxorubicin,Paclitaxel,Tamoxifen,Taxotere,Trastuzumab,Vinorebline,Zolendronic Acid
HCI-00779NTL6+Mixed carcinomaPositivePositivePositivePositivePositiveNegativeNot ReportedNot ReportedIVMetastasis45.00WhiteNoAromasin,Capecitabine,Carboplatin,Cyclophosphamide,Doxorubicin,Fulvestrant,Gemcitabine,Letrozole,Liposomal Doxorubicin,Paclitaxel,Tamoxifen,Taxotere,Trastuzumab,Vinorebline,Zolendronic Acid
HCI-009779812+AdenocarcinomaNegativeNegativeNegativeNegativeNegativeNegativeNot ReportedNot ReportedIVG3 (Poorly Differentiated)Metastasis42.00WhiteNo5-Fluorouracil,Alternative Medicine,Anastrozole,Cyclophosphamide,Fulvestrant,Methotrexate,Paclitaxel,Tamoxifen,Zolendronic Acid
HCI-010SUCWJ9+Infiltrating ductal carcinomaNegativeNegativeNegativeNegativeNegativeNegativeNot ReportedNot ReportedIVMetastasis47.00WhiteNoCapcitabine,Cyclophosphamide,Doxetaxel,Doxorubicin,Liposomal Doxorubicin,Paclitaxel,Zolendronic Acid,supraclavicular nodes and axilla
HCI-011Y0T0JDInfiltrating ductal carcinomaPositivePositiveNegativePositivePositiveNegativeNot ReportedNot ReportedIVMetastasis58.00Hispanic or LatinoNoArimidex,Capcitabine,Cyclophosphamide,Doxorubicin,Pacitaxel,chest wall and scar
HCI-0122SF730Infiltrating ductal carcinomaNegativeNegativePositiveNegativeNegativePositiveNot ReportedNot ReportedIVMetastasis49.00WhiteNo5-fluorouracil,Abraxane,Aldesleukin,Capecitabine,Capecitibine,Cyclophosphamide,Doxorubicin,Epirubicin,Herceptin,Interleukin 2,Lapatinab,Letrozole,Leucovarin,Methotrexate,Proleukin,Vinerolbine
HCI-013B6WNCG+Infiltrating lobular carcinomaPositivePositiveNegativePositivePositiveNegativeNot ReportedNot ReportedIVMetastasis46.00WhiteNoAbraxane,Aromasin,Capcitabine,Carboplatin,Cyclophosphamide,Doxorubicin,Fluorouracil,Gemcitabine,Letrozole,Leuprolide,Methotrexate,Paclitaxel,Tamoxifen,Zolendronic Acid
HCI-013EIB6WNCG+Infiltrating lobular carcinomaPositivePositiveNegativePositivePositiveNegativeNot ReportedNot ReportedIVMetastasis46.00WhiteNoAbraxane,Aromasin,Capcitabine,Carboplatin,Cyclophosphamide,Doxorubicin,Fluorouracil,Gemcitabine,Letrozole,Leuprolide,Methotrexate,Paclitaxel,Tamoxifen,Zolendronic Acid


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