PDX INSIGHTS
PIONEERING CANCER RESEARCH
Model Details

Patient Information for Model: TCCC-OS45

Model Contact
Model: TCCC-OS45
Model Contact: Nino Rainusso
Institution: TCH Sarcoma PDX Program
Email: ncrainuss@texaschildrens.org

Patient Information
Clinical Timeline


Clinical Information at Collection
Clinical Biomarkers/Mutations
Pathology Information at Collection

Model Information for Model: TCCC-OS45

Model Details - Initial Implantation of Patient Tissue
Mutations (Cancer Gene Census List)
Mutation data is currently not available.

CNV
There are no omics data for this model.


Histology Information for Model: TCCC-OS45
There are no histology images for this model.













Metastasis Information for Model: TCCC-OS45
 
Patient
PDX
Bone
Lung

Patient Treatment Information for Model: TCCC-OS45

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic ResponseReason Stopped
10Methotrexate, Doxorubicin, CisplatinNeoadjuvant15.6615.8362 daysPartial responseGood response (>90% tumor necrosis) Surgical resection (local control)
20Methotrexate, Doxorubicin, CisplatinAdjuvant15.9116.25124 daysNo evidence of diseaseEnd of therapy
30Ifosfamide /EtoposideAdjuvant20.2520.66150 daysNo evidence of diseaseEnd of therapy













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