PDX INSIGHTS
PIONEERING CANCER RESEARCH
Model Details

Patient Information for Model: TCCC-OS63

Model Contact
Model: TCCC-OS63
Model Contact: Nino Rainusso
Institution: TCH Sarcoma PDX Program
Email: ncrainuss@texaschildrens.org

Patient Information
Clinical Timeline


Clinical Information at Collection
Clinical Biomarkers/Mutations
Pathology Information at Collection

Model Information for Model: TCCC-OS63

Model Details - Initial Implantation of Patient Tissue
Mutations (Cancer Gene Census List)
Mutation data is currently not available.

CNV
There are no omics data for this model.


Histology Information for Model: TCCC-OS63
There are no histology images for this model.













Metastasis Information for Model: TCCC-OS63
 
Patient
PDX
Bone
Lung

Patient Treatment Information for Model: TCCC-OS63

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic ResponseReason Stopped
10Methotrexate, Doxorubicin, CisplatinNeoadjuvant10.6611.0124 daysPartial responsePoor response (5% tumor necrosis); progressed on neoadjuvant chemotherapySurgical resection (local control)
20Ifosfamide /EtoposideAdjuvant11.0811.2562 daysPartial responseMetastectomy (surgical resection lung metastasis)
30Ifosfamide /EtoposideAdjuvant11.3311.66120 daysProgress on chemotherapyProgression of disease ,died













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